Premenstrual Dysphoric Disorder (PMDD) is more than just a rough few days before your period.
Itās a severe, cyclical mood disorder that can disrupt your work, relationships, and sense of self. If you feel like you lose control of your emotions every month, and itās wrecking your ability to function, youāre not alone, and youāre not imagining it.
Many people with PMDD explore natural remedies as part of their treatment plan, and one of the most researched herbs for hormonal balance is the chaste tree, or Vitex agnus-castus.
Letās dive into the science behind PMDD, how hormones like prolactin and estrogen are involved, and how Vitex may help.
š What Is PMDD?
PMDD is a hormone-sensitive mood disorder that affects about 5% of people with menstrual cycles. It occurs during the luteal phase (the two weeks between ovulation and your period), and symptoms resolve within a few days after menstruation begins.
Core symptoms include:
Severe mood swings or rage
Depression or hopelessness
Anxiety or feeling "on edge"
Fatigue, insomnia, brain fog
Physical symptoms like bloating, breast pain, and headaches
What makes PMDD different from PMS is how much it interferes with daily life. You might find yourself calling in sick to work, picking fights with loved ones, or crying over things you normally shrug off. Some people even experience suicidal thoughts, a sign that medical help is urgently needed.
𧬠The Hormonal Puzzle Behind PMDD
While PMDD isnāt caused by abnormal hormone levels, it's likely due to an abnormal sensitivity to normal hormonal shifts, particularly estrogen, progesterone, and allopregnanolone (a calming neurosteroid derived from progesterone).
But thereās another hormone in the mix that doesnāt get as much attention: prolactin.
š Prolactinās Role in Hormonal Imbalance
Prolactin is best known for helping produce breast milk after childbirth, but it also interacts with your entire reproductive hormone system.
When prolactin is too high:
It suppresses GnRH (the hormone that starts the menstrual hormone chain reaction).
That lowers LH and FSH, which in turn reduces estrogen and progesterone.
Result: You might skip ovulation or have a short luteal phase, leading to symptoms like anxiety, mood swings, or irregular periods.
Lowering prolactin can:
Reboot your hormonal signaling
Increase or normalize estrogen and progesterone production
Support more regular cycles and better mood stability
šæ Vitex (Chaste Tree): A Natural Hormonal Regulator
Vitex agnus-castus: commonly known as chaste tree or chasteberry, has been used for centuries to help with hormonal issues. Modern research suggests that Vitex may work by lowering prolactin levels, which can rebalance other reproductive hormones.
How Vitex May Help PMDD:
Reduces prolactin, helping restore ovulation and healthy estrogen/progesterone balance
May improve symptoms of mood instability, breast tenderness, and bloating
Works best when taken consistently over 2ā3+ cycles
Common Forms:
Capsules or tablets (standardized extract is most researched)
Tinctures (liquid drops)
Teas (less potent but still used traditionally)
ā ļø Things to Keep in Mind
Vitex is not a quick fix. It may take a few cycles to notice changes.
It may not be appropriate if youāre already taking dopamine agonists or hormonal birth control
If you are breastfeeding, it may drop your milk supply.
For moderate to severe PMDD, Vitex may help as a complement to therapy, SSRIs, or cycle tracking, not always a standalone treatment.
ā Signs That Your Hormones Are Rebalancing
If Vitex and prolactin-lowering strategies are working for you, you may notice:
More predictable and regular cycles
Less intense mood swings or emotional crashes
Improved energy and sleep during the luteal phase
Fewer physical symptoms (like sore breasts or bloating)
š Final Thoughts
PMDD is real, valid, and deeply disruptive, but you are not powerless. Understanding how hormones like prolactininfluence your cycle gives you better tools to manage it. For many, Vitex offers a gentle, natural way to support hormone balance, especially when combined with good cycle tracking, nutrition, therapy, and, when needed, medication.









